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Transgender medicine

Spironolactone can be ineffective as an antiandrogen for many trans women

For trans women and transfeminine people who choose medical transition, one of the most common treatments is the use of…

Study: Spironolactone with medroxyprogesterone acetate suppresses testosterone in trans women more effectively than spironolactone alone

Disclaimer: I am not a medical professional and this is not medical advice. While spironolactone is one of the most…

Case series of trans women suggests HIV drug efavirenz may make oral estradiol less effective

Disclaimer: I am not a medical professional and this is not medical advice. Transgender women face a highly elevated prevalence…

New study on trans women’s developmental milestones: Self-awareness precedes disclosure by several years

I’ve previously criticized Lisa Littman’s study of the alleged condition of “rapid onset gender dysphoria” – since corrected as “perceived…

Trans women may face a higher risk of breast augmentation complications compared to cis women

Breast augmentation is a common gender-affirming surgery sought by transgender women and transfeminine people. Even with feminizing HRT, trans women…

Should elderly trans women continue taking HRT?

Disclaimer: I am not a medical professional and this is not medical advice. One question frequently asked by trans women…

Acne and body hair growth patterns in trans men on testosterone

Two recent letters to the editor in the Journal of the American Academy of Dermatology shed light on the degree…

How do spironolactone and cyproterone acetate compare for testosterone suppression in trans women?

Disclaimer: I am not a medical professional and this is not medical advice. Trans women are often understandably curious about…

New data on trans women’s estradiol/estrone ratios for different routes of administration of HRT

Disclaimer: I am not a medical professional and this is not medical advice. I’ve previously covered anecdotal reports from HRT…

Unsolved mystery: Trans women have significantly lower semen quality than cis men – before starting HRT

Sperm banking is the recommended method of fertility preservation for trans women prior to medical transition (Coleman et al., 2012),…