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Biology of transition

Recent report of potential fertility preservation in an early-transitioning trans girl: A new nuance, but no breakthrough yet

Disclaimer: I am not a medical professional and this is not medical advice. Previously: Transmasculine adolescent fertility breakthrough: Successful egg…

Starting puberty blockers at the onset of puberty is standard care for trans youth. Starting HRT could be, too.

Disclaimer: I am not a medical professional and this is not medical advice. If a transgender or gender-questioning youth is…

Second report of trans man undergoing successful fertility preservation without stopping testosterone – this time producing a viable embryo and live birth

Previously: Update on ovarian stimulation after testosterone use: Successful fertility preservation with less than a month’s interruption of HRT (April…

Early use of masculinizing steroid oxandrolone in trans boys can add 2 more inches of height compared to testosterone

Last year, I briefly covered an abstract by gender clinicians at Children’s Mercy Hospital describing the use of oxandrolone rather…

Transmasculine adolescent fertility breakthrough: Successful egg retrieval following puberty blockers since Tanner 2 and direct continuation to testosterone

Trans people who choose to transition medically may wish to maintain their reproductive potential following cross-sex hormone therapy or transition…

Additional details on the connection between transgender HRT and migraine headache patterns

Previously: Migraine headaches, trans people, and hormone therapy (September 2018) More on the relationship between hormone therapy and migraine in…

Trans men and transmasculine people on testosterone can grow prostate tissue

The general public’s knowledge of the nature of the physical changes induced by medical transition can be surprisingly spotty: trans…

“Biological sex”, empirical backfire: How transphobes gambled on COVID-19 – and lost

As the pandemic coronavirus has spread around the globe, the growing numbers of infections have revealed a surprising pattern: from…

Migraine headaches, trans people, and hormone therapy

From age 3 or 4, which is as far back as I can remember, I experienced chronic, frequent migraine headaches,…

New clinical findings from Dr. Will Powers: Role of estradiol/estrone ratio in the efficacy of feminizing HRT

(Epistemic status: Extremely tentative.) Dr. Will Powers, an HRT provider in Michigan who has possibly the coolest name ever, has…