Category Archives: Biology of transition

Starting puberty blockers at the onset of puberty is standard care for trans youth. Starting HRT could be, too.

Disclaimer: I am not a medical professional and this is not medical advice. If a transgender or gender-questioning youth is experiencing the distress of gender dysphoria about changes to their growing body, when – if at all – should they … Continue reading

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Second report of trans man undergoing successful fertility preservation without stopping testosterone – this time producing a viable embryo and live birth

Previously: Update on ovarian stimulation after testosterone use: Successful fertility preservation with less than a month’s interruption of HRT (April 2020) First report of trans man having successful fertility preservation without interrupting HRT (February 2021) Over the past few years, … Continue reading

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Early use of masculinizing steroid oxandrolone in trans boys can add 2 more inches of height compared to testosterone

Last year, I briefly covered an abstract by gender clinicians at Children’s Mercy Hospital describing the use of oxandrolone rather than testosterone as a part of masculinizing hormone therapy for adolescent trans boys, with the intention of both producing physical … Continue reading

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Transmasculine adolescent fertility breakthrough: Successful egg retrieval following puberty blockers since Tanner 2 and direct continuation to testosterone

Trans people who choose to transition medically may wish to maintain their reproductive potential following cross-sex hormone therapy or transition surgeries that remove the testes or ovaries. Trans adolescents who medically transition with GnRH agonist puberty blockers at the onset … Continue reading

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Additional details on the connection between transgender HRT and migraine headache patterns

Previously: Migraine headaches, trans people, and hormone therapy (September 2018) More on the relationship between hormone therapy and migraine in trans people (December 2019) Disclaimer: I am not a medical professional and this is not medical advice. A migraine headache … Continue reading

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