Category Archives: Biology of transition

“Biological sex”, empirical backfire: How transphobes gambled on COVID-19 – and lost

As the pandemic coronavirus has spread around the globe, the growing numbers of infections have revealed a surprising pattern: from China to Italy to the United States, men are more likely than women to contract the virus. And among those … Continue reading

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Migraine headaches, trans people, and hormone therapy

From age 3 or 4, which is as far back as I can remember, I experienced chronic, frequent migraine headaches, just as my mother and her father have had throughout their lives. These episodes of severe pain would often happen … Continue reading

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New clinical findings from Dr. Will Powers: Role of estradiol/estrone ratio in the efficacy of feminizing HRT

(Epistemic status: Extremely tentative.) Dr. Will Powers, an HRT provider in Michigan who has possibly the coolest name ever, has recently posted a slideshow outlining findings from his practice on the most effective approaches to feminizing hormone therapy for trans … Continue reading

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Your mileage may vary: Trans women and erectile function

One common question asked by trans women considering hormone therapy is how this may affect their ability to have penetrative sex. Antiandrogens and estrogen can impair erectile function, reducing spontaneous erections, responsiveness to sexual arousal, and nocturnal erections — an … Continue reading

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Fractals, not pyramids: Why “8th grade biology” isn’t enough

Previously: Chromosomes: Cis expectations vs. trans reality, How sex hormones work, and their use by trans people In the years I’ve spent covering gender topics on YouTube, I’ve occasionally encountered one particularly strange objection to the core principle of transness, … Continue reading

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