Category Archives: Transgender medicine

Spironolactone can be ineffective as an antiandrogen for many trans women

For trans women and transfeminine people who choose medical transition, one of the most common treatments is the use of hormonal medications to reduce testosterone levels and raise estrogen levels. By moving testosterone and estrogen levels into the normal female … Continue reading

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Study: Spironolactone with medroxyprogesterone acetate suppresses testosterone in trans women more effectively than spironolactone alone

Disclaimer: I am not a medical professional and this is not medical advice. While spironolactone is one of the most commonly used antiandrogens in feminizing hormone therapy, some trans women are still unable to achieve suppression of their testosterone levels … Continue reading

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Case series of trans women suggests HIV drug efavirenz may make oral estradiol less effective

Disclaimer: I am not a medical professional and this is not medical advice. Transgender women face a highly elevated prevalence of HIV infection, with Becasen et al. (2019) estimating that 14% of trans women in the United States are HIV-positive. … Continue reading

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New study on trans women’s developmental milestones: Self-awareness precedes disclosure by several years

I’ve previously criticized Lisa Littman’s study of the alleged condition of “rapid onset gender dysphoria” – since corrected as “perceived to show signs of a rapid onset of gender dysphoria” – on the grounds that its methodology, solely relying on … Continue reading

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Trans women may face a higher risk of breast augmentation complications compared to cis women

Breast augmentation is a common gender-affirming surgery sought by transgender women and transfeminine people. Even with feminizing HRT, trans women typically do not experience the same degree of breast growth as cisgender women (Reisman, Goldstein, & Safer, 2019), and studies … Continue reading

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