Category Archives: Endocrinology

4thWaveNow “ROGD parent” Brie Jontry doesn’t know what histrelin is

4thWaveNow, one of the three survey respondent recruitment sites for the badly flawed study of an alleged new “rapid onset gender dysphoria” condition, has long served as a clearinghouse for questionable notions about puberty-blocking medications used for transgender youth. These … Continue reading

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Migraine headaches, trans people, and hormone therapy

From age 3 or 4, which is as far back as I can remember, I experienced chronic, frequent migraine headaches, just as my mother and her father have had throughout their lives. These episodes of severe pain would often happen … Continue reading

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New study: Trends in usage of puberty-blocking implants in trans youth

Puberty-blocking medications for trans youth – and cis youth – come in many forms, ranging from GnRH analogues given as implants or injections, to a number of other generic oral medications. Of these, histrelin acetate implants, sold as Supprelin LA … Continue reading

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New study of the effects of feminizing hormones on testicular tissue in trans women

Most trans women on HRT are familiar with the phenomenon of “shrinkage”: atrophy of penile and testicular tissue, which typically becomes more pronounced the longer we’re on hormones. I’ve always wondered, as have many others, just what’s happening on the … Continue reading

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Additional information on transition treatment for trans women with BRCA1 or BRCA2 mutations

I’ve previously covered existing research on hormone therapy for trans women who are at an increased risk of breast cancer due to BRCA1 or BRCA2 mutations. As transitioning with estrogen induces the growth of breast tissue just as in cis … Continue reading

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