Category Archives: Endocrinology

New study: Trends in usage of puberty-blocking implants in trans youth

Puberty-blocking medications for trans youth – and cis youth – come in many forms, ranging from GnRH analogues given as implants or injections, to a number of other generic oral medications. Of these, histrelin acetate implants, sold as Supprelin LA … Continue reading

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New study of the effects of feminizing hormones on testicular tissue in trans women

Most trans women on HRT are familiar with the phenomenon of “shrinkage”: atrophy of penile and testicular tissue, which typically becomes more pronounced the longer we’re on hormones. I’ve always wondered, as have many others, just what’s happening on the … Continue reading

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Additional information on transition treatment for trans women with BRCA1 or BRCA2 mutations

I’ve previously covered existing research on hormone therapy for trans women who are at an increased risk of breast cancer due to BRCA1 or BRCA2 mutations. As transitioning with estrogen induces the growth of breast tissue just as in cis … Continue reading

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Nifty finds: Super-fast-acting hormone blockers used in Sweden

GnRH agonists are a class of drugs sometimes used as part of medical transition for trans people in order to block the sex hormones produced by their own bodies (Hembree et al., 2017). These are long-acting medications, typically given as … Continue reading

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Trans women with BRCA mutations: options for hormone therapy

The risk of breast cancer is a concern for trans women transitioning using estrogen and anti-androgens: they experience the growth of substantial breast tissue just as cis women do, and the use of estrogen could promote the growth of any … Continue reading

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