Disclaimer: I am not a doctor, and this is not medical advice. Do not take any medication without appropriate medical supervision.
Puberty suppression for transgender youth, developed in the 1990s, is one of the most important advances in the history of transition treatment. With the use of fully reversible GnRH analogue medications to halt natural puberty in appropriately diagnosed adolescents, and the later addition of cross-sex hormones, these youth are largely spared the development of gender-inappropriate sex characteristics: facial and body hair growth, voice deepening, and masculine facial structure and body shape in trans girls; and breast growth and hip widening in trans boys. As a result, many will not have to undergo costly and invasive procedures in adulthood to reverse the unwanted effects of original puberty, such as facial feminization surgery and chest reconstruction.
Treatment with puberty blockers is known to lead to measurably better outcomes for trans youth compared to transitioning in adulthood. Following use of puberty blockers and later treatment with cross-sex hormones and surgery, this population no longer experiences gender dysphoria, with overall psychological functioning comparable to their cisgender peers, and good quality of life (de Vries et al., 2014). Conversely, withholding puberty blockers from gender-dysphoric adolescents can result in worsening of dysphoria, depression, self-harm, and suicidality (Radix & Silva, 2014).
Because of the clear benefits of puberty blockers for trans youth, this treatment protocol is supported by the American Academy of Pediatrics, American Psychological Association, American Psychiatric Association, American Academy of Child and Adolescent Psychiatry, American College of Obstetricians and Gynecologists, and many more professional medical organizations. Blockers for trans kids are now offered by dozens of major hospitals and gender clinics across the United States.
However, many trans youth and their families still struggle to access these medically necessary treatments, often due to the expense of GnRH analogues and uneven insurance coverage of these medications for kids with gender dysphoria. But biology does not wait – these youth are in a critical developmental period, and foregoing puberty blockers can have lifelong consequences (Giordano, 2008). In light of these challenges, trans kids deserve more accessible and affordable options for blocking puberty. A number of recent studies have provided clinical evidence that inexpensive generic medications can be used in place of GnRH analogues for effective puberty suppression in trans youth, offering a potential alternative to more costly treatment. Continue reading →